If an underlying condition is responsible (liver disease, kidney disease, myeloproliferative disorder, or cancer), treating the underlying condition is the priority
However, the test membranes are also heavily stained orange by the 5-Amino-1MQ solution, demonstrating substantial interference from the sample itself
No tolerance development appears to occur, unlike many pharmaceutical compounds
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It requires a needle, which may lead to anxiety or discomfort, especially for individuals with a fear of needles